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Hii sir, I Wants to get the Information About the MICROBIAL GENETICS Subject of the TYBSC Course of the Mumbai University ?

[prince karak]

The University of Mumbai, informally known as Mumbai University, is one of the earliest state universities in India and the oldest in Maharashtra.


As you Asking for the Information About the MICROBIAL GENETICS Subject of the TYBSC Course of the Mumbai University the Syllabus is given below


MICROBIAL GENETICS
UNIT I DNA REPLICATION
1.1. Historical perspective— conservative, dispersive, semi-conservative, Bidirectional and semi discontinuous

1.2. Prokaryotic DNA replication– Details of molecular mechanism involved in Initiation, Elongation nd Termination

1.3. Enzymes and proteins associated with DNA replication- primase, helicase, topoisomerase, SSB, DNA polymerases, ligases, Ter and Tus proteins

1.4. Eukaryotic DNA replication--Molecular details of DNA synthesis, replicating the ends of the chromosomes

1.5. Rolling circle mode of replication

UNIT II MUTATION AND REPAIR

Mutation
2.1.a.Terminology:alleles, homozygous, heterozygous, genotype, phenotype, Somatic mutation, Germline mutation, Gene mutation, Chromosome mutation, phenotypic lag, hotspots and mutator genes

Fluctuation test.
2.1.c. Types of mutations: Point mutation, reverse mutation, suppressor mutation, frameshift mutation, conditional lethal mutation, base pair substitution,
ransition, transversion, missense mutation, nonsense mutation, silent mutation, neutral mutation, pleiotropic mutations.

Causes of mutation:Natural/spontan mutation--replication error,depurination, de
Induced mutation: principle and mechanism

illustrative diagrams for –
i. Chemical mutagens- base analogues, nitro hydroxyl amine, intercalating agents and alk agents.
ii. Physical mutagen
iii. Biological mutagen(only examples)
2.1.e. Ames test
2.1.f. Detection of mutants
2.2. DNA Repair
a. Mismatch repair,
b. Light repair
c. Repair of alkylation damage
d. Base excision repair
e. Nucleotide excision repair
f. SOS repair


TYBSC Microbiology Syllabus of the Mumbai University







Contact Details
University of Mumbai
M.G. Road
Fort
Mumbai-400 032

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