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Sathyabama Institute of Science and Technology B.Sc - Biotechnology SMB3201 Clinical Microbiology Syllabus SATHYABAMA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL OF BIO & CHEMICAL ENGINEERING SBB3201 BIOINFORMATICS L T P Credits Total Marks 3 0 0 3 100 UNIT 1 INTRODUCTION TO BIOINFORMATICS 12 Hrs. Introduction to bioinformatics: Definition, History, Objectives, Fields related to bioinformatics. Applications of Bioinformatics in the modern era UNIT 2 DATABASES 12 Hrs. Biological databases: Definition, Classification. Primary and secondary databases. Nucleotide databases, Protein sequence and structure databases, Structural Classification databases – SCOP and CATH UNIT 3 SEQUENCE ANALYSIS 12 Hrs. Introduction to sequence analysis and alignment - Global and Local Alignments, algorithm - Pairwise and Multiple sequence alignment. Tools for sequence alignments - BLAST, FASTA, Clustal W. Phylogenetic analysis UNIT 4 PROTEIN ANALYSIS 12 Hrs. Introduction to protein structure - primary, secondary and tertiary structures, domains, motifs and their uses. Secondary structure prediction - tools used. 3D structure prediction UNIT 5 CONCEPT OF GENE PREDICTION 12 Hrs. Exploring biological information: World Wide Web, Internet and its Uses in Bioinformatics Max Hours.60 END SEMESTER EXAMINATION QUESTION PAPER PATTERN Max. Marks: 100 Exam Duration: 3 Hrs. PART A: 10 questions of 2 marks each - No choice 20 Marks PART B: 2 questions from each unit of internal choice; each carrying 16 marks 80 Marks |
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