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SSSUTMS Sri Satya Sai University M.Pharma Pharmacology 3rd Sem Syllabus

Sri Satya Sai University of Technology and Medical Science Sehore,M.P
Semester III
MPH301T/MPL301T - Research Methodology & Biostatistics

UNIT – I
General Research Methodology : Research, objective, requirements, practical difficulties, review of
literature, study design, types of studies,strategies to eliminate errors/bias, controls, randomization,
crossover design, placebo, blinding techniques.

UNIT – II
Biostatistics: Definition, application, sample size, importance of sample size,factors influencing sample
size, dropouts, statistical tests of significance, type of significance tests, parametric tests ( students “t”
test, ANOVA, Correlation coefficient, regression), non-parametric tests (wilcoxan rank tests, analysis of
variance, correlation, chi square test), null hypothesis, P values, degree of freedom, interpretation of P
values.

UNIT – III
Medical Research: History, values in medical ethics, autonomy, beneficence,non-maleficence, double
effect, conflicts between autonomy and beneficence/non-maleficence, euthanasia, informed consent,
confidentiality, criticisms of orthodox medical ethics, importance of communication,control resolution,
guidelines, ethics committees, cultural concerns, truth telling, online business practices, conflicts of
interest, referral, vendor relationships, treatment of family members, sexual relationships, fatality.

UNIT – IV
CPCSEA guidelines for laboratory animal facility : Goals, veterinary care, quarantine, surveillance,
diagnosis,treatment and control of disease,personal hygiene,location of animal facilities to laboratories,
anesthesia,euthanasia,physical facilities, environment,animal husbandry,record keeping,SOPs,personnel
and training, transport of lab animals.

UNIT – V
Declaration of Helsinki: History, introduction, basic principles for all medical research, and additional
principles for medical research combined with medical care.