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Sathyabama Institute of Science and Technology B.Tech - Chemical Engineering SCHA3009 Drugs and pharmaceutical technology Syllabus

SATHYABAMA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL OF BIO AND CHEMICAL ENGINEERING

SCHA3009
DRUGS AND PHARMACEUTICAL
TECHNOLOGY
L T P Credits Total Marks
3 0 0 3 100

UNIT 1 INTRODUCTION 9 Hrs.
Pharmaceutical Industry, Drug discovery and Development of Drugs, Organic Therapeutic agents uses and Economics,
Physio chemical principles, Drug Metabolism and pharmacokinetics, Kinetic Studies and Action of drugs on Human Bodies,
antibiotics types.

UNIT 2 UNIT PROCESSES AND THEIR APPLICATIONS 9 Hrs.
Chemical Conversion Processes - Alkylation, Carboxylation, Condensation, Cyclisation, Dehydration, Esterification,
Halogenation Oxidation, Sulfonation, Complex Chemical Conversions and Fermentation.

UNIT 3 MANUFACTURING PRINCIPLES 9 Hrs.
Compressed Tablets, Wet Granulation, Dry Granulation or Slugging, Direct Compression, Tablet Presses, Formulation,
Coating Pills, Parental Solutions, Oral Liquid, Injections, Ointments, Standard of Hygiene and Manufacturing Practice
(GMP), Packing techniques and quality control.

UNIT 4 PRODUCT FORMULATION 9 Hrs.
Vitamins and other nutrients, Cold Remedies, Laxatives, Analgesics, External Antiseptics, Antacids, Biologicals, Hormones.

UNIT 5 ANALYSIS AND QUALITY CONTROL 9 Hrs.
Analytical Methods and Tests for various Drugs & Pharmaceuticals- principle, instrumentation and applications of UV/VIS
and IR spectroscopy, X-ray diffraction analysis, Fourier transform spectroscopy, chromatography principle and its types,
fluorimetry, polarimetry.
Max.45 Hrs.

COURSE OUTCOMES
On completion of the course, student will be able to
CO1 - Equipped with sound knowledge of drug development.
CO2 - Understand the conversion reactions involved in drug manufacture.
CO3 - Develop the various manufacturing principles and packing techniques.
CO4 - Understand the different products obtained during drug formulation.
CO5 - Apply the different analytical methods behind the drugs development.
CO6 - Enable a complete understanding of drug and pharmaceutical usage.

TEXT / REFERENCE BOOKS
1. Rawlnes E.A., Bentley’s Text Book of Pharmaceuticals, 7th Edition, Bailliere Tindalls, London, 2009.
2. Remingston, Pharmaceutical Sciences, 20th Edition, Mach Publishing Co., 2001.
3. Nita Pandit K., Introduction to Pharmaceutical Sciences, 4th Edition, Lipincott Williams & Wilkins, 2013.
4. James Swarbrick, Encyclopedia of Pharmaceutical Technology, 3rd Edition, Informa Healthcare Distribution, 2006.
5. Mark Saltzman.W., Drug delivery, Engineering Principles for Drug Therapy, 3rd Edition, Oxford University Press, 2011.

END SEMESTER EXAMINATION QUESTION PAPER PATTERN
Max. Marks:100 Exam Duration: 3 Hrs.
Part A: 10 Questions of 2 marks each - No choice 20 Marks
Part B: 2 Questions from each unit of internal choice; each carrying 16 marks 80 Marks