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Sathyabama Institute of Science and Technology B.Sc - BioChemistry SBB1602 Biopharmaceutical Technology Syllabus

SATHYABAMA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL OF BIO AND CHEMICAL ENGINEERING

SBB1602 BIOPHARMACEUTICAL TECHNOLOGY
L T P CREDITS TOTAL MARKS
4 0 0 4 100

UNIT 1 INTRODUCTION TO PHARMACEUTICALS 12 Hrs.
Definition of Drugs, Drug development process, Sources of Drugs - Plant, Animals, Microbes and Minerals. Different
dosage forms, Routes of drug administration.

UNIT 2 PHARMACODYNAMICS & PHARMACOKINETICS 12 Hrs.
Principles of basic and clinical pharmacokinetics and pharmacodynamics. Adverse drug reactions. Drug interactions,
Bioassay of drugs and biological standardisation of immuno-agents,

UNIT 3 DRUG MANUFACTURING PROCESSES 12 Hrs.
Good manufacturing practices, manufacturing facilities, Production & analysis of Biopharmaceuticals. Characterization
and quality control of biotech derived products: impurities present in biotechnology derived products, foreign
contaminants

UNIT 4 PHARMACEUTICAL PRODUCTS 12 Hrs.
Therapeutic categories such as laxatives - analgesics - non steroidal contraceptives - external antiseptics - and
antacids

UNIT 5 DRUG DELIVERY SYSTEMS 12 Hrs.
Biomaterials and their Applications Controlled and sustained delivery of drugs. Biomaterial for the sustained drug
delivery. Liposome mediated drug delivery. Drug delivery methods for therapeutic proteins.
Max Hours.60

TEXT / REFERENCE BOOK
1. Gary Walsh, Biopharmaceuticals: Biochemistry & Biotechnology, John Wiley & Sons Ltd. 2004.
2. Remington’s Pharmaceutical sciences, 17th Edition, Mark Publications & Company, 1985.
3. Leon Lachman, Lea & Febiger U.S, Theory and Practice of Industrial Pharmacy, 3rd Edition, 1986.
4. Pharmaceutical Biotechnology: Drug Discovery and Clinical Applications, Second Edition Editor(s): Prof. Dr.
Oliver Kayser, Prof. Dr. Heribert Warzecha, First published:18 April 2012
5. Textbook of Pharmaceutical Biotechnology Chandrakant Kokate, SS Jalalpure, Pramod H.J Elsevier Health
Sciences, 27-Apr-2016.

END SEMESTER EXAMINATION QUESTION PAPER PATTERN
Max. Marks : 100 Exam Duration : 3 Hrs.
PART A : 10 questions of 2 marks each - No choice 20 Marks
PART B : 2 questions from each unit of internal choice; each carrying 16 marks 80 Marks