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Sathyabama Institute of Science and Technology B.Tech - BioTechnology SBTA3005 Medical Biotechnology Syllabus

SATHYABAMA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL OF BIO AND CHEMICAL ENGINEERING

SBTA3005 MEDICAL BIOTECHNOLOGY
L T P Credits Total Marks
3 0 0 3 100

UNIT 1 BASIC CONCEPTS AND TOOLS 9 Hrs.
Understanding human body, Genomics, Proteomics, Genetic disorders, Drugs, Pharmacogenomics, Pharmacokinetics.

UNIT 2 SIGNALING MECHANISMS 9 Hrs.
Receptor mediated signal transduction – primary messenger – hormones and drugs- secondary messenger and
neurotransmitters. G- Protein coupled receptors – cyclic AMP –calcium ions – Nitric oxide (NO) – prostaglandin and inositol
triphosphates.

UNIT 3 DIAGNOSTICS 9 Hrs.
Hematology, Biochemistry (Serum & Tissue), Histology (Biopsy and Autopsy) and Endocrinology. Diagnosis of Bacteria
(Mycobacterium), DNA virus (HBV/H1N1), RNA virus (HIV/HCV), Parasite (Malaria).

UNIT 4 TREATMENT AND PREVENTION 9 Hrs.
Traditional medicine (AYUSH), Chinese and Modern medicine, Antibacterial, Antiviral, Antibiotics, use of interferon,
immunomodulators. Active and passive immunization, vaccines and toxoids, Food as medicine-Nutraceuticals.

UNIT 5 THERAPEUTIC DEVELOPMENTS AND DRUG DESIGNING 9 Hrs.
Basics of Regenerative medicine, Nanomedicine, Combinatorial antibody designing, Gene therapy, Anti sense therapy-
RNAi. Drug designing process, receptor–ligand interaction, ligand docking-Bioinformatics tools.
Max.45 Hrs.

COURSE OUTCOMES
On completion of course, student will able to
CO1 - Develop an ability to use appropriate knowledge to identify and analyze the molecular basis of disease & emerging
technology.
CO2 - Conduct investigations of complex problems by methods that include appropriate experiments, analysis and
interpretation of data and synthesis of information in order to reach valid conclusions
CO3 - Design solutions for complex, open-ended problems that meet specified needs with appropriate attention to health
and safety risks
CO4 - Create, select, apply, adapt, and extend appropriate techniques, resources, and modern tools
CO5 - Work effectively as a member and leader in teams, preferably in a multi-disciplinary setting
CO6 - Address their own educational needs in a changing world in ways sufficient to maintain their competence and to
allow them to contribute to the advancement of knowledge in Medical & Pharmaceutical fields

TEXT / REFERENCE BOOKS
1. Judit Pongrácz and Mary Keen, Medical Biotechnology, Churchill Livingstone Elsevier, 2009.
2. Devlin T.M., Textbook of Biochemistry with Clinical correlations, John Wiley and Sons, 2010
3. Arthur C. Guyton and John Edward Hall, Textbook of medical physiology, Elsevier Saunders 2006.
4. Aparna Rajagopalan, Fundamentals of Medical Biotechnology, Ukaaz publications 2006.
5. Jogdand S.N., Medical Biotechnology, Himalaya publications, 2011.

END SEMESTER EXAMINATION QUESTION PAPER PATTERN
Max. Marks: 100 Exam Duration: 3 Hrs.
Part A: 10 Questions of 2 marks each - No choice 20 Marks
Part B: 2 Questions from each unit of internal choice, each carrying 16 marks 80 Marks